Berberine HCl is a compound extracted from several plants and has become one of the more widely studied natural ingredients for metabolic and glucose health.

The research behind it most often uses doses in the range of 900mg to 1500mg daily, split across multiple servings — well above what a single once-daily capsule sharing space with two other ingredients could plausibly contain.

Because Valiora doesn't disclose the individual dose, there's no way to know how it compares to the amounts used in that research. It's also worth knowing berberine can interact with certain medications, which is why the brand recommends checking with a pharmacist first.

Where it sits in the formula: one of three named ingredients in Valiora's proprietary blend, alongside Green Tea (Camellia sinensis) Leaf Extract, Apple Cider Vinegar.